Measuring Dermatology, Approach and Gadget for User-independent Ultrasound Measurement of Skin Thickness
The research summed up here includes the style of a device and processing strategy to obtain and construct 3D volumetric ultrasound data of the hand and arm. The Repeated Skin Density Measurement (RSTM) Device moves a high frequency ultrasound probe linearly in 3 axes in a water tank and images an immersed arm. These images are combined into an ultrasound volume, the skin layer segmented, and the density extracted. One specific application is determining progression of scleroderma, a skin thickening illness. Present measurement strategies for scleroderma development rely on subjective scientific viewpoint, lack quantitative rigor, are intrusive, and frequently measure parameters besides density that are less carefully connected to the development of scleroderma. The current diagnostic procedure evaluates skin thickness based on a single ultrasound image taken by a user holding the ultrasound probe. The imagery that arises from the instrumentation and analysis in this thesis is utilized to create objective maps of skin density to measure the progression of skin-thickening diseases, and can also be utilized to observe tendons, ligaments, and the other soft tissue structures of the hand. By taking a look at density over the surface area of the hand and arm, a more robust metric of development of scleroderma and other soft tissue illness can be obtained.
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