Emphasizes: Ultrasonography (United States) is an easily offered non-invasive tool beneficial for the detection of musculoskeletal and soft tissue masses United States is increasingly used for directing procedures and biopsies that are indicated when histopathology will customize patient management. FNAB does not consists more in the simple aspiration performed with 22-23 G needle attached to a 20 mL non reusable syringe. Several Menghini type semi-automatic biopsy devices with small-caliber (18 to 21 G) needles provide high-quality histopathologic specimens. Abstract: Ultrasonography (United States) is a readily offered non-invasive tool useful for the detection of musculoskeletal and soft tissue masses. Although X-Ray is often the first imaging study for examining both bone and soft tissue lesions, and magnetic resonance imaging and computed tomography are obligatory in lesions staging, United States is significantly utilized for the early assessment of musculoskeletal and soft-tissue masses and for assisting treatments and biopsies. Surgical biopsy or fine needle goal biopsy (FNAB) is needed to determine the nature of any sore. FNAB is a low cost technique, more secure and less traumatic than an open surgical biopsy. Considerable issues are unusual, mainly associated to the site of biopsy. Knowledge of indicators, limitations, physiological and pathological access, sufficient technical competence in US imaging and in intervention skills are the crucial factors of the suitable and safe use of FNAB. By now, the role of FNAB in musculoskeletal diseases is questionable and there is still a heated debate in the scientific community.
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